4-Acetoxy-N,N-dimethyltryptamine (also known as 4-AcO-DMT, 4-Acetoxy-DMT, O-Acetylpsilocin, and psilacetin) is a novel psychedelic substance of the tryptamine class. It is chemically similar to psilocybin, the active ingredient in psilocybin mushrooms (magic mushrooms). It belongs to a group known as the substituted tryptamines which act by stimulating serotonin receptorsin the brain. The synthesis of 4-AcO-DMT was first reported in 1963 by Albert Hofmann and Franz Troxler. However, its properties were not examined and no further studies were carried out. A 1999 paper by David E. Nichols suggested it as a useful alternative to psilocybin for pharmacological research. Reports of human use began to surface following its appearance on the online research chemical market in the 2010s.
Changa is a DMT-infused smoking blend. Extracts from DMT-containing plants are combined with a blend of different herbs. And ayahuasca vine and/or leaf to create a mix that is 20–50% DMT, akin to a smokeable ayahuasca. Changa was created by Australian Julian Palmer in 2003-2004 and named when he ‘asked’ for a moniker for the drug during an Ayahuasca session. The substance became highly popular in Australia in the mid 2000s, but its widespread introduction outside of Australia appears to be dated to the Boom Festival in Portugal in 2008 where many of the first online accounts of its use outside of Australia occur.
3,4-Methylenedioxymethamphetamine, commonly known as ecstasy, is a psychoactive drug primarily used as a recreational drug. The desired effects include altered sensations and increased energy, empathy, and pleasure. When taken by mouth, effects begin after 30–45 minutes and last 3–6 hours
3,4-Methylenedioxymethamphetamine, commonly known as ecstasy, is a psychoactive drug primarily used as a recreational drug. The desired effects include altered sensations and increased energy, empathy, and pleasure. When taken by mouth, effects begin after 30–45 minutes and last 3–6 hours.
Mescaline (3,4,5-trimethoxyphenethylamine) is a naturally occurring psychedelic alkaloid of the phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin. It occurs naturally in the peyote cactus (Lophophora williamsii), the San Pedro cactus (Echinopsis pachanoi), the Peruvian torch (Echinopsis peruviana), and other members of the Cactaceae plant family. It is also found in small amounts in certain members of the Fabaceae (bean) family, including Acacia berlandieri. However those claims concerning Acacia species have been challenged and have been unsupported in additional analysis.